I really like the smoothing options in Krita. It is the best I know. Even better than the one in Manga Labo that was my favourite before. I have used Krita and smoothing in this small illustration using my first "own" pen, a little rough variant of an ordinary inking pen. I have also started to get used to all new shortcuts (I am used to Painter) and find it easy to grip the keys with my left hand every time. I don't need to make any custom settings. I use the colour picker (Ctrl), the sizing of the tool (Shift), move canvas (Spacebar) and the rotate canvas (Shift+Spacebar). One shortcut I have not found yet is the one to reset the rotated canvas back to 0 again. Is there a shortcut for that?

Cool feedback
Yes, there is a shortcut to reset canvas rotation ; it's a bit hard to discover I must admit : numpad 5
( with numpad 4 and 6 rotating discretely the canvas )

Ordinary '5' -- not numpad -- works as well