I'm hoping someone can help, I downloaded the latest update and whenever I have the program up, my screen begins flashing off and on. This only happens when the program is active, regardless of if I have my tablet hooked up or not.

I am running windows 10, and did not have this problem in the version I was using beforehand.

Sounds a bit like a botched graphics driver restarting itself? What graphics card are you using? Have you tried updating your graphics driver?

If you can, please open 3.2.1 (https://download.kde.org/stable/krita/3.2.1/krita-3.2.1-x64.zip) and copy the contents from Help->Show system information for bug reports.