Hi every one,

I like to share for gamers that use Neon and like to play League of Legends. I got it run here

I used:

-Play On Linux https://www.playonlinux.com/en/
-Wine version 1.9.2-staging-LOL3.

There are some tricks in the moment of the installation:

1º Update your drivers/modules of graphic card;
2º Don't open the game in the end of installation, clear checkbox "run league of legends laucher" THIS IS VERY IMPORTANT;
3º In settings of League of Legends on PlayOnLinux go to last tab "Miscellaneous" or "Several" (My native language is Portuguese and not English HAHAHA! ) fist option "replace leak mouse" select ENABLE.

Done!.

Image of the game running here: http://imgur.com/5ga9HXW

I followed this tutorial, use the translator to understand:
http://boards.br.leagueoflegends.com/pt/c/taverna-do-gragas/xv6Ms9vI-tutorial-como-instalar-o-league-of-legends-no-linux-passo-a-passo-2016?show=flat&page=2